Correlation of Whole Blood Cell Morphology on Electrical Impedance Spectroscopic Characteristics on the Severity Level of Ischemic Stroke Patients

Abstract

This paper discusses the influence of peripheral blood smear morphology methods on the electrical impedance spectroscopic characteristics of blood samples from ischemic stroke patients. In this study, there were 26 blood samples, consisting of a control group with 5 blood samples and a group of ischemic stroke patients with 21 samples with varying degrees of severity. The methods used are electrical impedance spectroscopy (EIS) and whole blood cell morphology methods. The EIS method was carried out using the BISDAQ tool and application, and results were obtained in the form of Bode Plot, Bode Phase Plot, Nyquist Plot, and measurement data values in the form of Ms. Excel. Meanwhile, the Morphological method is carried out by making a peripheral blood smear, then viewing and obtaining an image using a digital microscope, and then counting the number of cells using the Image Raster application. Based on the results of the method carried out, the correlation can be seen to conclude that whole blood cell morphology greatly influences the characteristics of EIS and determines the severity of ischemic stroke patients.